fbpx

Andropause

Andropause is a condition that is associated with the decrease in the male hormone testosterone. It is unlike menopause in that the decrease in testosterone and the development of symptoms is more gradual

Background

male-intro@2x-8
Male age 55

General Symptoms

  • Sarcopenia (Loss of muscle mass)
  • Osteoporosis
  • Loss of Libido
  • Constipation & Erective Dysfunction
  • Mood Swings
  • Sweat at Night Saggy Cheeks
Andropause BG

Diagnosis

Improved mental health from elevated MCHC value by 4%.

Mean Corpuscular Haemoglobin Concentration (MCHC) refers to the average haemoglobin in the red blood cells. Haemoglobin is the protein molecule that carries oxygen to the tissues within the body.

During Treatment – November 2017

The normal range for MCHC is between 33-36 g/dl.

Before Treatment – July 2017


Patient’s MCHC is slightly under standard at 32.3 g/dl suggesting that he has signs of deficiency in Vitamin B12 which increases risk of having depression, paranoia and delusions, memory loss, incontinence, loss of taste and smell. Skerrett, 2013

After Treatment – October 2018


Patient’s MCHC has improved by 4% and return back to normal range.

Outcome


Normalising MCHC helps improving patient’s mental health.

Lowered risk of osteoporosis and heart disease by restoring Vitamin B & D balance.

Studies have shown that high homocysteine is a risk factor of heart disease. Ganguly, 2015; Wierzbicki, 2007

The maximum value of homocysteine for normal people is <8 μmol/l.

Before Treatment – July 2017


Patient’s homocysteine level is at 11.1 μmol/l exceeded almost 39% of maximum reference value. This suggests a high deficiency in Vitamin B, particularly Vitamin B12 and folic acid.

Besides, Patient’s low level of Vitamin D (22.5 ng/ml; normal range 30-80) increases the risk of osteoporosis.

During Treatment – November 2017


Patient’s homocysteine level is reduced by 26% after four months from 11.1 μmol/l to 8.2 μmol/l. While Patient’s Vitamin D is raised by 3.53 times.

Reduced inflammation by 50%

During Treatment – July 2017

Inflammation level is under good condition as patient’s level is at 0.4 mg/l which is within standard.

After Treatment – October 2018

Patient’s inflammation level improved by a reduction of 50%.

Treatment & Outcome

Treatment


Aug 2017

4 types of oral supplements
Nov 2017

6 types of oral supplements
Oct 2018

10 types of oral supplements

Summary


1. Improved mental health from elevated MCHC by 4%.
2. Reduced risk of osteoporosis by raising Vit D 3.53 times.
3. Lowered risk of heart disease by reducing homocysteine 26%.
4. Inflammation level improved by a reduction of 50%.
5. All symptoms show signs of improvement.

Department of Health (2017) Men’s healthline – andropause
https://www.chp.gov.hk/en/static/80026.html

Ganguly, P., Alam, S.F. (2015) Role of homocysteine in the development of cardiovascular disease. Nutrition Journal. 14:6 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326479/

Schwarz, E.R., Phan, A., Willix, R.D. (2011) Andropause and the development of cardiovascular disease presentation – more than an epi-phenomenon. Journal of Geriatric Cardiology. 8(1):35-43 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390065/

Skerrett, P.J. (2013) Vitamin B12 deficiency can be sneaky, harmful. Harvard Health Publishing. https://www.health.harvard.edu/blog/vitamin-b12-deficiency-can-be-sneaky-harmful- 201301105780

Singh, P. (2013) Andropause: Current concepts. Indian Journal of Endocrinology and Metabolism. 17: S621-629 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046605/

Wierzbicki, A.S. (2007) Homocysteine and cardiovascular disease: a review of the evidence. Diabetes & Vascular Diesease Research. 4(2):143-150 https://www.ncbi.nlm.nih.gov/pubmed/17654449

Advanced Cancer Research (2003) Natural killer cells and cancer
https://www.ncbi.nlm.nih.gov/pubmed/14710949

American Cancer Society (2016) Viruses that can lead to cancer
https://www.cancer.org/cancer/cancer-causes/infectious-agents/infections-that-can-lead-to-cancer/viruses.html

Billett, H.H. (1990) Haemoglobin and haematocrit. Clinical methods: the history, physical, and laboratory examinations
https://www.ncbi.nlm.nih.gov/books/NBK259/

Campo, E., Swerdlow, S.H., Harris, N.L., Pileri, S., Stein, H., Jaffe, E.S. (2011) The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Journal of American Society of Hematology. 117(19):5019-5032
https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC3109529/#

Coy, J.F. (2017) EDIM-TKTL1/Apo10 blood test: an innate immune system based liquid biopsy for the early detection, characterization and targeted treatment of cancer. International Journal of Molecular Sciences. 20:18(4)
https://www.ncbi.nlm.nih.gov/pubmed/28425973

Encyclopaedia Britannica (2019) Neurotransmitter
https://www.britannica.com/science/
neurotransmitter

Ginaldi, L., Martinis, M.D., Matutes, E., Farahat, N., Morilla, R., Catovsky, D. (1998) Levels of expression of CD19 and CD20 in chronic B cell leukaemias. Journal Clinica of Pathology. 51:364-369
https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC500695/pdf/jclinpath00266-0020.pdf

Grimm, M., Schmitt, S., Teriete, P., Biegner, T., Stenzl, A., Hennenlotter, J., Muhs, H.J., Munz, A., Nadtotschi, T., Konig, K., Sanger, J., Feyen, O., Hofmann, H., Reinert, S., Coy, J.F. (2013) A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells. BMC Cancer. 4:13:569 https://www.ncbi.nlm.nih.gov/pubmed/24304513

Ko, Y.H. (2015) EBV and human cancer. Experimental & Molecular Medicine. 47(1):e130 https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC4314581/

Lange, C.A.K, Tisch-Rottensteiner, J., Bohringer, D., Gottfried, M., Schwartzkopff, J., Auw-Hadrich, C. (2012) Enhanced TKTL1 expression in malignant tumours of the ocular adnexa predicts clinical outcome. Ophthalmology. 119(9):1924- 9
https://www.ncbi.nlm.nih.gov/pubmed/22658715

Madu, A.J., Ocheni, S., Ibegbulam, OG., Aguwa, E.N., Madu, K.A. (2013) Pattern of CD4 T-lymphocyte values in cancer patients on cytotoxic therapy. Annals of Medical and Health Science Research. 3(4):498-503
https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC3868113/

Martel, J. (2018) Healthline: T cell count
https://www.healthline.com/health/t-cell-count

National Cancer Institute (2018) NCI Dictionary of Cancer Terms- cancer

https://www.cancer.gov/publications/
dictionaries/cancer-terms/def/cancer

National Cancer Institute (2018) NCI Dictionary of Cancer Terms – complete blood count
https://www.cancer.gov/publications/
dictionaries/cancer-terms/def/complete-blood-count

National Cancer Institute (2018) NCI Dictionary of Cancer Terms – malignancy
https://www.cancer.gov/publications/
dictionaries/cancer-terms/def/malignancy

National Cancer Institute (2018) NCI Dictionary of Cancer Terms – thrombocytes
https://www.cancer.gov/publications/
dictionaries/cancer-terms/def/thrombocyte

National Kidney Foundation (2017) Creatinine: what is it?
https://www.kidney.org/atoz/content/what-creatinine

Ollila, J. & Vihinen, M (2005) B cells. The International Journal of Biochemistry & Cell Biology. 37(3):518-23
https://www.ncbi.nlm.nih.gov/pubmed/
15618007

Thompson, M.P. & Kurzrock, R. (2004) Epstein-Barr virus and cancer. Clinical Cancer Research. 10(3):803-21 https://www.ncbi.nlm.nih.gov/pubmed/
14871955

Troussard, X., Cornet, E. (2017) Hairy cell leukemia 2018: update on diagnosis, risk stratification, and treatment. American Journal of Hematology 92(12):1382-1390
https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC5698705/

Wu, J., Lanier, L.L. (2003) Natural killer cells and cancer. Advances in Cancer Research. 90:127-56 https://www.ncbi.nlm.nih.gov/pubmed/
14710949

University of Rochester Medical Center (2019) What are red blood cells?
https://www.urmc.rochester.edu/encyclopedia/
content.aspx?ContentID=34&ContentTypeID=160

Vazzana, N., Spadano, R., Sestili, S., Toto, V., Falorio, S., Catinella, V., Angrilli, F., Dragani, A. (2004) Hairy cell leukaemia and venous thromboembolism: a case report and review of the literature. Blood Transfusion. 12(2):276- 279
https://www.ncbi.nlm.nih.gov/pmc/articles/
PMC4039712/

Viver, E., Tomasello, E., Baratin, M., Walzer, T., Ugolini, S. (2008) Functions of natural killer cells. Nature Immunology. 9(5):503-10
https://www.ncbi.nlm.nih.gov/pubmed/
18425107

* The case studies of PRAXISKLINIK AM SCHLOSSPARK/Miskawaan Health Group represent carefully & individually assessed clients’ treatments following extensive testing – they are only to be used as examples of treatments and not as a guideline for treatment.
Scroll to Top